How mRNA-based therapies could change the world, Biden’s renewables boost, and the semi shortage
Thomas Rice, portfolio manager for the Perpetual Global Innovation Share Fund provides his regular wrap of technology, innovation, and finance news.
Published on April 7, 2021
By
Thomas Rice
Greetings!
Hope you had a relaxing Easter break.
Here’s your wrap of the latest technology, innovation, and finance news.
? Health
One fascinating area of healthcare right now is the potential development of mRNA-based therapies beyond the COVID-19 vaccines. The Atlantic explores how mRNA technology could change the world.
But mRNA’s story likely will not end with COVID-19: Its potential stretches far beyond this pandemic. This year, a team at Yale patented a similar RNA-based technology to vaccinate against malaria, perhaps the world’s most devastating disease. Because mRNA is so easy to edit, Pfizer says that it is planning to use it against seasonal flu, which mutates constantly and kills hundreds of thousands of people around the world every year. The company that partnered with Pfizer last year, BioNTech, is developing individualized therapies that would create on-demand proteins associated with specific tumors to teach the body to fight off advanced cancer. In mouse trials, synthetic-mRNA therapies have been shown to slow and reverse the effects of multiple sclerosis.
“I’m fully convinced now even more than before that mRNA can be broadly transformational,” Özlem Türeci, BioNTech’s chief medical officer, told me. “In principle, everything you can do with protein can be substituted by mRNA.”
This study paves the way for research into drugs that can target cancer stem cells. “In the future, the DN gel could be used to enhance cancer cell type diagnosis and to produce personalized medicines, which could improve the prognosis of cancer patients,” said Shinya Tanaka.
The same team has now created life forms that self-assemble a body from single cells, do not require muscle cells to move, and even demonstrate the capability of recordable memory. The new generation Xenobots also move faster, navigate different environments, and have longer lifespans than the first edition, and they still have the ability to work together in groups and heal themselves if damaged.
“It’s one thing to prove that you can empty the bin—that’s interesting on one level,” says Goldberg. But it’s another thing to do it quickly and reliably. Goldberg says that Ambi Robotics’ system can do this sorting job twice as fast as humans. He adds that its products are not meant to replace human workers, but to supplement them. “This is just one piece of a pipeline that happens with packages,” Goldberg says. “And all throughout that pipeline, there’s steps that need human intervention.”
“The autonomy itself is a core technology, in my view. If you sort of step back, the car, in a lot of ways, is a robot. An autonomous car is a robot. And so there’s lots of things you can do with autonomy. And we’ll see what Apple does,” Cook said in an interview released Monday with Kara Swisher on the “Sway” podcast.
“We investigate so many things internally. Many of them never see the light of day. I’m not saying that one will not,” Cook added.
In a blog post explaining his decision to resign as CEO, but remain with Waymo as an advisor, Krafcik wrote, “now, with the fully autonomous Waymo One ride-hailing service open to all in our launch area of Metro Phoenix, and with the fifth generation of the Waymo Driver being prepared for deployment in ride-hailing and goods delivery, it’s a wonderful opportunity for me to pass the baton to Tekedra and Dmitri as co-CEOs.”
Plus, a developer of autonomous truck technology, raised another $220 million on top of the $200 million they raised in February.
The Chinese technology firm, which is the world’s third-largest smartphone maker, is jumping into an incredibly competitive space in China.
Not only is Xiaomi competing with established automakers in the country, such a Geely and Warren Buffet-backed BYD, but also upstarts such as Nio and Xpeng Motors.
The project is intended to store energy so that the energy produced by the solar farm can be used during the night as well as during the day, and Cupertino says the project will store enough energy to “power over 7,000 homes for one day.” Apple plans to share some of what it learns from the project with other companies, executives have said.
“Steve Stoute and UnitedMasters provide creators with more opportunities to advance their careers and bring their music to the world,” Apple executive Eddy Cue said in a statement. “The contributions of independent artists play a significant role in driving the continued growth and success of the music industry, and UnitedMasters, like Apple, is committed to empowering creators.”